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Professor Dale Wigley and his team are finding out what happens when the DNA in a cell is damaged, and how the cell deals with it. If DNA damage is not repaired correctly, mistakes occur in important genes which can lead to cancer.Professor Wigley studies bacteria grown in the lab to investigate DNA repair. Bacteria are a simple model system and easier to work with than human cells. Understanding the DNA repair processes in bacteria will help Professor Wigley and his team gain insight into the similar, more complex, processes at work in human cells.Learning more about how cells repair damage to their DNA could lead to new ways to prevent or treat cancer in the future.

 Mr Ciaran McKeown

Mr Ciaran McKeown

 Liz McCormack  Completed a BAppSci in Australia and a number of years later  a part-time MSc in Biomolecular Organization at Birkbeck College.  Liz worked at the Institute of Cancer Research for 14 years in Professor Keith Willison’s Lab before joining the Wigley Lab in  2011.

Liz McCormack

Completed a BAppSci in Australia and a number of years later  a part-time MSc in Biomolecular Organization at Birkbeck College.  Liz worked at the Institute of Cancer Research for 14 years in Professor Keith Willison’s Lab before joining the Wigley Lab in  2011.

 Valerie Good  She is the manager of the Structural Biology Baculovirus expression facility at Imperial College.   

Valerie Good

She is the manager of the Structural Biology Baculovirus expression facility at Imperial College.

 

 Ms Lorraine Ocloo  Graduated with a 2.1 in Biomedical Science BSc (IBMS accredited) before working as a trainee Molecular Diagnostic scientist at The Rayne Institute, King’s College Hospital. Following this, she went on to work at the Institute of Cancer Research (ICR) as a Lab Assistant.

Ms Lorraine Ocloo

Graduated with a 2.1 in Biomedical Science BSc (IBMS accredited) before working as a trainee Molecular Diagnostic scientist at The Rayne Institute, King’s College Hospital. Following this, she went on to work at the Institute of Cancer Research (ICR) as a Lab Assistant.

 Kaiying Cheng   Graduated from Zhejiang University, China. I’m here to learn to be a scientist

Kaiying Cheng

Graduated from Zhejiang University, China. I’m here to learn to be a scientist

 Laura Griffin  She is a postdoctoral researcher using structural biology techniques to  investigate human DNA repair complexes

Laura Griffin

She is a postdoctoral researcher using structural biology techniques to  investigate human DNA repair complexes

 Martin Wilkinson  Post-Doc with experience in protein expression, purification and high-resolution structural studies including both X-ray crystallography and Electron Microscopy. Currently working on complexes involved in DNA repair.

Martin Wilkinson

Post-Doc with experience in protein expression, purification and high-resolution structural studies including both X-ray crystallography and Electron Microscopy. Currently working on complexes involved in DNA repair.

 Dr Oliver Willhoft  Earned his PhD in Structural Biology from the Institute of Structural and Molecular Biology (ISMB) in London. As a post-doc in the Wigley lab, he has been working on chromatin remodelling complexes of the INO80 family

Dr Oliver Willhoft

Earned his PhD in Structural Biology from the Institute of Structural and Molecular Biology (ISMB) in London. As a post-doc in the Wigley lab, he has been working on chromatin remodelling complexes of the INO80 family