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Professor Xiaodong Zhang's research programme focuses on unravelling the mechanisms of macromolecular machines using a range of structural biology techniques including X-ray crystallography and cryo-electron microscopy. She is particularly interested in large macromolecular assemblies involved in DNA processing, as well as the AAA (ATPase Associated with diverse cellular Activities) protein family. At present, her research focuses on three main areas: key components in DNA damage response, transcriptional regulation in bacteria, structure and mechanism of multifunctional p97

 Ciaran McKeown 

Ciaran McKeown 

 Fuzhou YE  Research associate, I am currently working on bacterial RNA polymerase and the transcription machinery, elucidating how the full transcription machinery assembly from structural and biochemical perspectives.

Fuzhou YE

Research associate, I am currently working on bacterial RNA polymerase and the transcription machinery, elucidating how the full transcription machinery assembly from structural and biochemical perspectives.

   Dr Luke A. Yates    A post-doctoral research associate and faculty research fellow (July 2018) in the Zhang lab. I completed my D.Phil in Clinical Medicine at Oxford University (Merton College), but my research career has predominantly focused on investigating protein function using structural biology as a means to provide a mechanistic understanding in life and in disease.    Twitter:  @Yates_luck

Dr Luke A. Yates

A post-doctoral research associate and faculty research fellow (July 2018) in the Zhang lab. I completed my D.Phil in Clinical Medicine at Oxford University (Merton College), but my research career has predominantly focused on investigating protein function using structural biology as a means to provide a mechanistic understanding in life and in disease.  

Twitter: @Yates_luck

 Rafael Ayala  PhD student in Xiaodong Zhang’s group working on the INO80 chromatin remodeler

Rafael Ayala

PhD student in Xiaodong Zhang’s group working on the INO80 chromatin remodeler

 Robert Glyde  He is a PhD student in Xioadong Zhang's lab studying the mechanisms of transcription initiation in bacteria. He mostly use cryo-electron microscopy to look at the structures of protein-DNA complexes at different points of the initiation pathway.

Robert Glyde

He is a PhD student in Xioadong Zhang's lab studying the mechanisms of transcription initiation in bacteria. He mostly use cryo-electron microscopy to look at the structures of protein-DNA complexes at different points of the initiation pathway.

 Thomas McCorive  He Completed his PhD in biochemistry at Queen's University Belfast in 2012. With expertise on the structural biology of disease-associated proteins he is now investigating BRCA2 and its complexes using cryo electron microscopy                                                           

Thomas McCorive

He Completed his PhD in biochemistry at Queen's University Belfast in 2012. With expertise on the structural biology of disease-associated proteins he is now investigating BRCA2 and its complexes using cryo electron microscopy                                                           

 Yueru Sun                        

Yueru Sun

 

 

 

 

 

 

 

 

 Joshua Kaplan  Research Assistant for the Zhang Group. He holds a MRes in Biomedical Research from Imperial College London, focused on the Molecular Basis of Human Disease, and a BSc in Biomedical Sciences from the University of Sussex.

Joshua Kaplan

Research Assistant for the Zhang Group. He holds a MRes in Biomedical Research from Imperial College London, focused on the Molecular Basis of Human Disease, and a BSc in Biomedical Sciences from the University of Sussex.

 Qiao Gao. PhD Student  Project on Structural vaccinology for Chikungunya vaccine design

Qiao Gao. PhD Student

Project on Structural vaccinology for Chikungunya vaccine design

 Min Hao  Visiting Researcher 

Min Hao

Visiting Researcher 

 Liu Xiaojiao   Research on purification of RtcR protein, functional assay and structural biology

Liu Xiaojiao

Research on purification of RtcR protein, functional assay and structural biology